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“Nowhere is Safe”, said Sir David King, former UK Chief Scientific Advisor, of the violent heat in Canada, in the July of 2021, when temperatures soared to 48-49 celsius, in the western hemisphere. There is no doubt that the urgency for mitigating the effects of climate change is going to require exponential disruptions to eliminate our reliance on fossil fuels.

One such start-up, developing breakthrough solutions in replacing fossil fuel with hydrogen as a clean energy source is Ossus Biorenewables. The start-up has developed an AI-powered, intelligent bioreactor, the OB HydraCel, which accesses carbon in the wastewater from process industries and supplies these industries with on-demand, on-site hydrogen gas.

Ossus, founded in 2017, is a Bangalore based green hydrogen start-up, directly addressing the need for a carbon-free source of heat in process industries. What differentiates them from others in the clean energy space, is their use of waste carbon as the feedstock for green hydrogen. Typically their technology is directed at the petrochemical, steel, textile, paints, pharmaceutical, fertiliser, ammonia and other chemical industries.

Ossus Biorenewables is among the 12 startups that are part of the sixth edition of Qualcomm Design in India Challenge (QDIC) – an initiative to encourage design houses and product companies to invent useful and innovative hardware products designs incorporating Qualcomm SoC platforms and technologies. The startup is bestowed with the opportunity to convert its design submissions into workable prototypes under the mentorship of industry experts, utilizing the Qualcomm® Innovation Lab infrastructure.

“When we pitched to be a part of QDIC 2021, we were already looking to make a transition from IoT-based automatic to ML-based autonomous control systems for the HydraCel. What Qualcomm did for us, was to exponentially accelerate this transition. By integrating a Qualcomm chip set with inbuilt machine learning capabilities, we could combine the best of biology and artificial intelligence to create a paradigm shift in the hydrogen space. Our bioreactors are now able to intelligently correct for any changes in the wastewater quality at a client’s site and consistently deliver hydrogen gas. QDIC took this one step forward by incentivizing IP filing and we now have two patents filed as a result of our participation in the program. The HydraCel is at the bleeding edge of clean energy and Industry 4.0 and currently producing hydrogen for one of India’s largest steel manufacturers at Jamshedpur.” She states.

We spoke to Dr. Suruchi Rao, the co-founder of Ossus Biorenewables, who explained about the existential crisis of climate change that is pushing the energy transition across the process and manufacturing sectors and driving a market for their technology in India and globally.

Electrolysis of water, simply put, is the splitting of water into its constituent molecules hydrogen and oxygen in dedicated reactors known as electrolyzers. For Ossus believes, there are three key stressors when defining only water splitting and electrolyzers as the source of green hydrogen.

One, splitting a molecule as stable as hydrogen requires extremely high power inputs. Two, is the manufacturing of electrolyzers and the high costs associated with using rare earth metals such as Iridium and Platinum as electrode material. Three, is the use of fresh water or ultra-high purity water for electrolysis, which would cause a resource constraint of enormous proportions. At Ossus, they are mitigating all these stressors via the OB HydraCel device. It is an intelligent green hydrogen reactor which requires as little as 0.76 kWHr for every kilogram of hydrogen it produces, as opposed to the average of 50-55 kWHr required by the best electrolyzers for the same volume. Ossus Biorenewables and their intelligent bioreactor, the OB HydraCel, become game changers, using designer microbes to utilise waste water for hydrogen gas production.

By using sustainable materials as catalysts, without the use of iridium or platinum, Ossus is manufacturing intelligent bioreactors indigenously, which is extremely important for a country like India that aims to meet its target of 10 gigawatts electrolyzer capacity.

“Most importantly, with the OB HydraCel and its ability to tap into wastewater as a feedstock, there is enhanced circularity brought to the green hydrogen economy. By coupling water treatment to the production of green hydrogen, we have reduced the stress on local fresh water resources. Nowhere is this more evident at the moment than in India, with its newly released National Hydrogen Policy”, explains Suruchi.

“We are combining the best of biology and artificial intelligence to create a paradigm shift in the hydrogen space. Our bioreactors are easy to install, unmanned and scaled out, allowing process industries to set up their own pace when it comes to increasing hydrogen capacity at an industrial site. The HydraCel is at the bleeding edge of clean energy and Industry 4.0 and currently producing hydrogen for one of India’s largest steel manufacturers at Jamshedpur,” she adds.

The interdisciplinary team and their principle approaches to tackle their clients’ problems are the reasons for Ossus’ rapid traction across the industry in India. They have now set their eyes on raising funds for expanding exponentially across multiple industries, with several 1000 kg (1 ton) per day installations, in India and then moving to Europe to capture the billion dollar hydrogen market.

For any further information\query you can write to us at Co-innovate@nasscom.in

Figure 1 Divya Sriram & Sujoy Deb, Co-Founders

The epoch-making discoveries in the field of molecular diagnostics have remarkably enhanced the healthcare and life-science industry. This advancement has helped clinicians get a comprehensive analysis of the human genes to understand disorders and diseases and opt for the best treatment for patients. In this era of modern yet cost-effective next-generation molecular diagnostics techniques, , healthcare institutions around the world are seamlessly optimizing patient care, enhancing testing accuracy, and selecting appropriate and personalized medicine to treat infectious & genetic diseases, cancer, diabetes, and so forth.

Giving thoughts to the increasing demand for molecular diagnostic approaches especially after the onset of COVID 19, co-founders Divya Sriram & Sujoy Deb envisaged to set up a deep-tech &  biotech startup-D-NOME, disrupting molecular diagnostics. A cancer molecular biologist and a genomics expert, the dynamic duo have combined their experiences in molecular diagnostics and Next-generation Sequencing to create a room-temperature LAMP technology. Their amalgamated passion and vision brought into being an innovative D-LAMP platform technology that is based on advanced molecular tools and synthetic biology. This endeavour is enabling advanced molecular diagnostics like RT-PCR & Genomics (NextGenSeq) to be affordable, scalable and accessible to all.

The company is virtually incubated at Center of Excellence – IoT & AI, Gurugram, which is a Joint initiative of the Ministry of Electronics & IT (MeitY), Govt. of Haryana, and NASSCOM.

How is D-Nome solving the problems of diagnostic labs?

D-LAMP’s room temperature RT-PCR technology removes the dependency on RT-PCR machines. It is a 1-reagent and 1-step system that helps labs conduct tests in just 30 minutes without sourcing multiple reagents or skilled technicians. This is especially designed for diagnostic labs & hospitals to help them reduce their time, effort, and operational costs invested in the entire molecular diagnostics workflow. “Going forward we also aim to expand D-LAMP into point-of-care testing at low-cost settings due to its ease of use and affordability”, explains Divya Sriram, CEO, D-NOME.

Diagnostic accuracy has been a major concern for molecular tests and D-Nome has been at the forefront in managing this crisis. “D-LAMP works on a novel room-temperature technology based on the principles of LAMP isothermal amplification. Its patent-pending reagent composition, is what makes it a reliable, specific, and cost-effective molecular diagnostic platform that has been cross-validated with industry gold-standards. It is world’s first room-temperature LAMP technology,” states Sujoy Deb, Co-founder & CTO, D-Nome.

Interestingly, D-LAMP technology platform allows for use in multiple adjacent markets including livestock screening, veterinary diagnostics, and agriculture molecular testing.

D-Nome’s strength of will is paving their way to success!

D-Nome is steadily climbing the ladder of success and the impact it has created in the ecosystem is quite commendable. In just one year of formation, the startup has received the recognition and support of some of the premier biotech incubation centres (AIC-CCMB, C-CAMP & IKP) and organizations like C-CAMP InDx (indigenization of diagnostics) and NASSCOM. They are recipients of the respected BIRAC –BIG Grant and are pre-seed invested by London-based investors Entrepreneur First.

D-Nome has participated and won several innovative challenges, bagging distinguished awards in India and international platforms. D-nome was selected from over 3000+ applicants in National Bio Entrepreneurship Competition 2021 and won the-Syngene & Cytiva Prizes. Recognized as a deep-tech pioneer, D-nome is the winner of the prestigious Hello Tomorrow Global Deep-Tech Challenge 2021 (for the medical and pharma category), held in Paris, France, selected from over 4000 applicants worldwide with a challenging 8-month long selection process including multiple technical rounds.

At present, D-Nome team is burning the midnight oil to introduce its innovative D-LAMP product and is currently raising their seed-round for R&D, expansion and product launch. They are looking forward to potential clients and successful partnerships, and more.

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Prashant Warier, CEO and Founder, Qure.ai

Healthcare is one of the fundamental pillars of society. However, over the past 2 years, rapidly rising COVID-19 infection caseloads have placed global health systems under pressure, often threatening to overwhelm available resources. Now more than ever, the role of technology, specifically Artificial Intelligence (AI) solutions, in assisting medical practitioners and alleviating the extraordinary burden placed on them, is coming to the fore.

Qure.ai is a home-grown AI solutions provider that is disrupting the ‘status quo’ in diagnostics by enhancing imaging accuracy and improving health outcomes with the assistance of AI. We tap deep learning technology to automate interpretation of radiology exams for time and resource-strapped healthcare professionals, enabling faster diagnosis and speed to treatment. Our goal is to make healthcare more accessible and affordable to patients worldwide.

In mid-2020, we started working with secondary care hospitals in rural and semi-urban areas of India, that was delivering last mile healthcare connectivity. Some of these are in isolated tribal areas but host close to 100,000 OPD visits annually. With scarce resources, they were already handling a significant burden of Tuberculosis (TB), but had to swiftly respond to COVID-19 as well. Most did not have RT-PCR testing facilities nearby, increasing the diagnosis time by days, and exposing the limited staff to COVID-19.

Imaging procedures have been established to be the most effective method of evaluating the lung state of COVID-19 patients as well as measuring the disease’s rate of progression. The use of chest X-rays as a first investigation prior to confirmatory testing could be done because these hospitals have chest X-ray facilities. However, the scarcity of trained chest physicians and limited access to teleradiology services meant analysing chest X-rays could take days, leaving little time for reporting. We realised that our technology could help physicians in these hospitals in caring for vulnerable populations despite their resource constraints

In partnership with ACT Grants, we undertook a project to implement qXR, our AI algorithm for chest X-ray interpretation, in 20 select charitable and government hospitals across 14 states in India. The objective was to strengthen COVID-19 response by scaling up the usage of qXR for triage and critical care management. qXR was used across the following use cases:

AI for COVID-19 Triage

qXR was used for triage or immediate isolation based on chest X-rays, which played an important role before confirmatory tests, screening for infectious diseases when dedicated radiology services were unavailable.

AI for COVID-19 Surveillance

In several hospitals, qXR was used in chest X-ray surveillance mode to track asymptomatic or incidental COVID-19 cases that might otherwise be missed. Based on the screening result, they were deferred till diagnosis or handled with appropriate additional safety measures in case of an emergency.

AI for COVID-19 Progression Monitoring

In hospitals with COVID wards, qXR was used as an objective disease progression monitoring tool. At sites where digital X-Ray setups were not available or integration was not possible, Qure.ai’s app qTrack was used by the hospital team to take a photo of the chest X-Ray film. The digitised photo would be analysed by Qure.ai’s AI software to check for COVID-19 indications.

AI for Other Clinical Uses

Over the course of the project period, qXR’s role evolved, and included its use as a training tool for junior doctors, being used to help ensure safety of clinical and hospital staff, its use as one of the mechanisms to correct for false negatives of the RAT, and for Tuberculosis screening and other lung ailments.

The journey of Qure.ai

Established in 2016, the company has grown in leaps and bounds in terms of revenue, clients and geographical presence. The startup’s dedicated effort to build out-of-the-box healthcare technology solutions that can help health professionals to improve their practices and deliver quality patient care has won Qure.ai many prestigious awards including the Nvidia Social Innovation Award and Forbes Awards for Innovation.

In the year 2020, this Mumbai-based healthcare startup initiated a partnership with the world’s leading pharmaceutical firm, AstraZeneca A.Catalyst Network through the India Sweden Healthcare Innovation Centre. The motive behind this collaboration is to stimulate the integration of ingenious artificial intelligence solutions and analyse the deep learning algorithms to support the early detection of lung cancer in patients. This will help healthcare providers extend absolute care, reduce mortality rates, and boosts patient outcomes. Both the organization share the vision of exploring the market opportunities in India, Latin America, Asia, the Middle East, and Africa.

Qure.ai banded together with leading organizations like Stanford University, the Mayo Clinic, and the Massachusetts General Hospital to leverage AI and fabricate medical technologies. In India, it has collaborated with NITI Aayog, Piramal Foundation’s Piramal Swasthya initiative, and PATH NGO to nurture and further the advancement of radiology and pathology across the country. The company is said to have utilized above 3.5 million data to condition an AI algorithm that ensures accurate diagnostics, enhancing patient care.

The company is supported by investors like fractal, Sequoia, and MassMutual. It has raised around $16 million in financing for AI. Qure.ai’s Brain CT has bagged funding from the NHS as well. It has a huge research partners and customers list that includes big giants such as MAX Healthcare, AWS, FujiFilms, Azure, Intel, and others.

For any further information\query you can write to us at Co-innovate@nasscom.in

We all want to live and work in an environment that makes us feel safe and secure. All this while, the concept of residing in a safe building was to have strong walls, roofs, and other basic amenities. With technology entwined in every aspect of our lives and the realization of creating a resilient human world led to the adoption of leading digital technologies for building smart cities became imperative. Streamlining and technologically empowering the buildings is necessary to circumvent the pitfalls and save energy.

The growing need to enrich operational efficiency, monitor energy usage, boost productivity and augment occupants’ comfort encouraged the use of intelligent monitoring and regulatory systems such as the Building Information Modeling techniques and the Building Management System (BMS). BMS or the Building Automation System (BAS), is a centralized and computer-based network that helps smart buildings attain power efficiency, minimize the amount invested in operational and maintenance processes.

The demand for BMS has been skyrocketing recently which makes it one of the leading and profitable sectors for budding go-getters who are excited to explore market possibilities. Garima Bhardwaj and Gaurav Bali, creators of Enlite `-a Mumbai based tech startup are on a mission of developing world’s first Operating System for Real estate – Know Your Building ™ a unique combination of wireless building management system and service digitization.

Enlite is the outcome of Garima & Gaurav’s forethought of enabling the standardization of building through advanced technologies. This reformation could help complement residences’ standards of living. These disruptive solutions play a crucial role in surveilling the air quality, security, building temperature, hygiene maintenance, surveillance and other. The best utility of building standardization is keeping a tight rein on the wastage of natural resources.

Enlite is one of the 12 startups that are part of the sixth edition of Qualcomm Design in India Challenge (QDIC) – an initiative to encourage design houses and product companies to invent useful and innovative hardware products designs incorporating Qualcomm SoC platforms and technologies. The startup is bestowed with the opportunity to convert its design submissions into workable prototypes under the mentorship of industry experts, utilizing the Qualcomm® Innovation Lab infrastructure.

The startup was previously also selected to be a part of Qualcomm’s well-rounded mentorship program QWEIN (Qualcomm Women Entrepreneurs India Network) – a six-month curriculum offering women-led startups opportunities and mentorships that helps them unbar the potential of their business.

While working with OYO, Garima was assigned the responsibility of organizing, enhancing, and customizing the hotels of various types and sizes as per the guidelines set by the company and the requirement of the customers. During this vocation, Garima came close to understanding the gaps that exist in the real estate industry and how non-standardized it is. On the other note, technologies that have the potential to address the glitches are high-priced and esoteric which the small and medium sections face difficulty to snap up and operate. The idea of bringing in cost-effective and technically advanced solutions that can lead the change and promote standardization in the industry, kindled Garima & Gaurav to lay the cornerstone of Enlite. It took years of diligence, discipline, hard work, and excessive research in giving shape to the vision of disrupting the building automation industry.

“Our collective vision is to brainstorm ideas to invigorate building standardization. The aim is to develop a platform that thinks up and extends the latest, comprehensive, user, environment, and pocket-friendly building management system to support the small and mid-sized commercial infrastructures with real-time building level monitoring and controlling. Our system is designed to conserve energy & save energy bills, reduce operational cost, automate efficiency, automate and digitize all manual processes, contribute and complement the endeavor of building a smart building that ensures safety, security, comfort to the occupants,” said Gaurav Bali, Co-Founder, Enlite.

Headquartered in Mumbai, the startup has built a one-of-a-kind Operating System for real estate (Know Your Building™) using deep technologies like Artificial Intelligence and IoT.  The interoperable Operating System along with wireless energy-efficient and non-invasive universally integrable device endow companies with effortless and systematic processes for monitoring and managing mechanical, electrical, electromechanical and soft services of their establishments. Know Your Building™ (KYB) is the progression of traditional building management and automation systems into an information system. Using KYB every stakeholder in a building can derive value, from every point of a building like never before.

Their other flagship offerings are Building health management, Asset management, Contactless Access Controls equipped with hardware and sensors that detect parameters such as electricity usage, air quality, and monitor different areas of the building services, and so on. The team of Enlite had worked together to make their devices more touchless to cater to the COVID requirement, helping companies and occupants reside in a robust and benign environment.

When Enlite introduced its concept in the Indian market, the results were astonishing. Companies from across verticals were keen to learn and adopt this disruptive technology to enhance efficiency. The startup has initiated partnerships with some of the leading firms from the APAC & MENA region and is launching is first overseas establishment in Qatar in January 2022 and is looking at 1 million sq.ft. of its operating system deployment in the first quarter of 2022.

For its future ventures, this AI-driven startup will be launching the next version of its operating system with more features to automate and digitize every possible type of a building and is looking at expanding into a couple of more countries in middle-east towards the second half of next year.

For any further information\query you can write to us at Co-innovate@nasscom.in

Heart attack is the leading cause of death around the world. Health officials’ concern deepens as cardiovascular disease is affecting the youngsters along with the adults. They are seen to be suffering and complaining from heart-related issues. Sedentary lifestyle, dietary choices, hypertension are some of the major causes that have heightened the risk factors for heart attacks among the young.

Still and all, awareness about heart attack symptoms, self-care, early and accurate diagnosis can help people prevent or reduce the cause of cardiovascular diseases. Tricog Health has been at the forefront to save the lives of young and adults by empowering physicians with technology solutions. The cornerstone of Tricog Health is laid by Dr. Charit Bhograj. He along with healthcare and technology pundits Dr. Zainul Charbiwala, Dr. Udayan Dasgupta, and Abhinav Gujjar worked towards addressing the challenges caused due to the inaccessibility of appropriate preliminary diagnosis (ECG). The pillars of the startup brought their expertise together in discovering and developing cutting-edge solutions that support Virtual Cardiology Services to remote clinics.

Known to be the world’s largest predictive healthcare analytics firm, Tricog Health uses advanced AI algorithms to improve survival rates of heart attacks by decreasing the average time between symptoms and treatment. The teams of Tricog Health has designed devices such as:

InstaECG: A cloud-connected ECG service that analyzes, interprets and provides Cardiac expert Certified ECG reports in 10 minutes.

InstaEcho: This helps doctors to get quick and accurate echocardiogram diagnosis in matter.

Tricog Health’s medical contrivances have proven to be instrumental in saving treatment time, expediting the process and accuracy of remote care, and saving lives. The startup has been extending free ECG Interpretation within 10 minutes, 24×7 throughout the COVID 19 pandemic.

Tricog health is among the six startups that were selected by GE Healthcare under its India Edison Accelerator Programme-a first-of-its-kind initiative that aims to co-create technology solutions that will enable healthcare providers to deliver precision health, aiming to accelerate the transformation of the healthcare industry. The startup is enabled to work with healthcare industry experts from within and outside GE on their product development for six months; build and scale their technologies for the targeted market.

GE Healthcare had set up a partnership with Tricog Health in the year 2015 and ever since then, they embarked on the mission of identifying and mitigating roadblocks facing healthcare quality and delivery. Tricog was the first startup on-boarded on the GE Healthcare accelerator program five. eight. This partnership led to the creation of Cloud-connected ECG devices in indigent areas to help physicians detect heart complications. The solution has reached the remotest of areas and saved thousands of patients. In a span of six years, this Bangalore-based startup has deployed its products and solutions in more than 14+ countries, served 6 million+ patients, saved 200 K+ lives, and empowered above 12Kmedical professionals worldwide. It has a strong client base that includes customers like Apollo Hospitals, Metropolis, Manipal Hospital, Max Healthcare, Neuberg diagnostics, Fortis, and many others.

In 2020, this AI-driven health-tech firm received a funding of $10.5 million in a Series B funding round from UTEC – The University of Tokyo Edge Capital, Japan; Aflac Ventures, LLC, Japan; TeamFund, USA and Dream Incubator, Japan. After a year of its establishment, the company has raised an undisclosed amount in Series A funding from Inventus Capital Partners, Blume Ventures, and a group of angel investors (2016).

Tricog laid the cornerstone of its journey in 2015, and in its six years tenure it brought off awe-inspiring researches and innovations. The outstanding initiatives have won the startup prestigious awards and recognition. It has been honoured by the NASSCOM Artificial Intelligence Game Changer Award 2018 & AI for Good, conducted by the Centre of Excellence in association with the Government of Karnataka. The Ayushman Bharat PM-JAY Startup Grand Challenge selected Tricog Health for its best startup in the category, “Ensuring Quality of Care.” It has also won first place in the ET Startup Awards 2019, Accenture Healthtech Innovation Challenge (Regional Finalist 2018), a Software product of the Year -Express IT Award 2019, Draper Venture Network for the Most Innovative DVN Company2018, and more.

Tricog Health remains positive about exploring healthcare technology to shape the future of health and healthcare.

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The past decade has seen a massive technology explosion in medical sciences which has made patient care simpler and efficient. Healthcare innovators are playing a crucial role in driving innovation in the healthcare industry that has stimulated new opportunities, boosted proficiency, and helped the sector address the challenges.

Tech-enthusiasts Dr. Aneesh Sathe, Dr. Kaveh Taghipour, and Dr. Rajasa Jialdasani jumped in the sublime bandwagon of leveraging the state-of-art-technologies to revamp the methods observed for the diagnosis and treatment of cancer. They ventured into the domain with the end in view to discover the innovative technological leeway and approaches to enhance histopathology diagnosis of cancer, making it faster, accurate and affordable. Qritive is helping patients and doctors breathe a sigh of relief by developing clinical-grade decision support systems that assist the delivery of insightful, meticulous and personalized care.

Qritive’s concept of unleashing the power of Artificial Intelligence and image analytics to further the digital pathology and the research associated with it has precipitated innovative approaches to curate AI-powered solutions for the pathology labs and get regulatory approvals for them. Furthermore, Qritive also excels in building customized applications that empower pathologists to straightaway share data on the cloud including images captured by phone, camera-mounted microscopes, or whole-slide scanners.

Qritive created a unique CE-IVD marked vendor-agnostic digital pathology platform intending to dynamize the digitization and remodel the pathology lab workflow, enhance telepathology and support remote diagnosis. Through Pantheon^TM the company aims to enable AI analysis of whole-slide imaging in pathology and encourage the development of reports that are verifiable and well-grounded. The platform’s AI modules assist pathologists to study a range of diseases by helping to detect and grade cancers. Qritive is working with research institutions on R&D projects for building predictive digital biomarkers.

Qritive is one of the six startups selected by GE Healthcare under its India Edison Accelerator Programme-a first-of-its-kind initiative that aims to co-create technology solutions that will enable healthcare providers to deliver precision health, aiming to accelerate the transformation of the healthcare industry. The startup is enabled to work with healthcare industry experts from within and outside GE on their product development for six months.

Established in 2017, Qritive has come a long way! The startup has created a niche in the healthcare ecosystem and has successfully positioned itself as a ground breaking health tech startup in the international market. It has established partnership with major hospitals and senior pathologists in Singapore and South East Asia, and leading companies such as DELL, Philips, AWS, Google Cloud, Singapore General Hospital, and many more.

Its out-of-the-box initiatives have won many titles and awards. From making to the list of Top 10 companies MedTech Innovator Asia Pacific 2020 to getting featured by National Research Foundation Singapore, selected by Elevator (NRF) 2017, receiving Class A Medical Device registration from Health Sciences Authority Singapore (HSA) to obtaining CE Mark for Digital Pathology and getting certified as ISO 13485 international standard for design, development, manufacture, distribution, and installation of software medical devices across the globe, Qritive has earned it all! The company is backed by Singapore and US VC funds and the largest hospitals in the region.

Over and above these, the company has emerged as one of the winners of the second edition of NASSCOM CoE’s Healthcare Innovation Challenge (HIC 2.0).

For the time to come, Qritive anticipates to further explore technology to make cancer diagnostic more advanced and accessible. It aims to see itself as the leader in the realm of cancer diagnostics.

For any further information\query you can write to us at Co-innovate@nasscom.in